U.S. President Donald Trump announced on Wednesday that the United States will withdraw from dozens of international and United Nations entities, deepening his administration’s retreat from multilateral institutions it says run counter to U.S. interests.

In a memo sent to senior administration officials, Trump listed plans to exit 35 non-U.N. groups and 31 U.N.-linked entities. Among the most prominent is the U.N. Framework Convention on Climate Change (UNFCCC), widely described as the bedrock global climate treaty and the parent agreement to the 2015 Paris climate accord.

The move would make the United States the first country to walk away from the UNFCCC. The U.S. already skipped last year’s annual U.N. climate summit for the first time in three decades, signaling its growing disengagement from global climate negotiations.

Trump also said the United States will quit UN Women, the U.N. agency promoting gender equality and women’s empowerment, as well as the U.N. Population Fund (UNFPA), which focuses on family planning and maternal and child health in more than 150 countries. U.S. funding for UNFPA was cut last year.

“For United Nations entities, withdrawal means ceasing participation in or funding to those entities to the extent permitted by law,” the memo said. Trump has already sharply reduced voluntary U.S. contributions to most U.N. agencies.

The White House said the targeted organizations promote “radical climate policies, global governance, and ideological programs that conflict with U.S. sovereignty and economic strength.” It added that the withdrawals are part of a broader review of all international intergovernmental organizations, conventions and treaties involving the United States.

Trump’s decision reflects his long-standing skepticism toward multilateral institutions, particularly the United Nations. Since starting his second term a year ago, he has halted U.S. engagement with the U.N. Human Rights Council, extended a freeze on funding for the Palestinian relief agency UNRWA, quit UNESCO and announced plans to leave the World Health Organization and the Paris climate agreement.

Other bodies on the withdrawal list include the U.N. Conference on Trade and Development, the International Energy Forum, the U.N. Register of Conventional Arms and the U.N. Peacebuilding Commission.

A spokesperson for U.N. Secretary-General Antonio Guterres did not immediately respond to a request for comment to Reuters. Critics warned that leaving key global forums could reduce U.S. influence over international rules and policies, while the administration maintains the move will end taxpayer funding for institutions it says operate inefficiently or contrary to American priorities.