At least five people were killed Sunday when an Amazon Prime Air cargo plane ran off a runway while landing at Miami International Airport and collided with several vehicles, according to local officials.
Prime Air Flight 7598 overshot the airport’s diagonal runway shortly before 2 p.m. EDT and struck vehicles on the ground, officials said at a news conference.

A view of an Amazon Prime Air cargo plane that airport officials said overran a runway at Miami International Airport, in Miami, Florida, U.S., September 6, 2026. REUTERS/Marco Bello
Miami-Dade Fire Chief Ray Jadallah said five people were injured, including three who remained in critical condition. At least two people were trapped inside vehicles hit by the aircraft, while the pilot and co-pilot were trapped inside the plane.
Authorities did not immediately identify those who died.
More than 60 rescue units and approximately 200 personnel responded to the crash, Miami-Dade Fire Rescue said. An active fuel leak from the aircraft was still being handled by emergency crews later Sunday afternoon.
Airport Operations Partially Resume
Miami International Airport stopped all flights immediately after the crash. By Sunday evening, two of the airport’s four runways had reopened.

A law enforcement officer gestures at the site of an Amazon Prime Air cargo plane that airport officials said overran a runway at Miami International Airport, in Miami, Florida, U.S., September 6, 2026. REUTERS/Marco Bello
The aircraft was a 32-year-old Boeing 767-300 freighter that had previously been used as a passenger aircraft by several airlines between 1994 and 2015, according to flight-tracking service Flightradar24.
The plane had departed San Juan, Puerto Rico, and was operated for Amazon by cargo airline 21 Air, an Amazon spokesperson said.
Flightradar24 reported that the aircraft was traveling at 112 knots, or about 129 mph, when it left the usable portion of the runway.

Damaged vehicles after airport officials said an Amazon Prime Air cargo plane overran a runway at Miami International Airport, in Miami, Florida, U.S., September 6, 2026. REUTERS/Marco Bello
Photographs taken after the crash showed the aircraft resting with its nose on the ground and its tail raised. Scorch marks were visible on the right side of the plane.
Federal Investigation Underway
The National Transportation Safety Board has sent a team led by Chairwoman Jennifer Homendy to investigate the crash. The agency said it would hold its first media briefing in Miami on Monday.
Amazon spokesperson Kelly Nantel said the company was working with local authorities to determine what happened and that its immediate priority was the safety and care of those affected.

A view of the Amazon Prime Air cargo plane that airport officials said overran a runway at Miami, Florida, U.S., September 6, 2026, in this screengrab from a social media video. Rohan Ellis/via REUTERS THIS IMAGE HAS BEEN SUPPLIED BY A THIRD PARTY. MANDATORY CREDIT. NO RESALES. NO ARCHIVES. THIS PICTURE WAS PROCESSED BY REUTERS TO ENHANCE QUALITY. AN UNPROCESSED VERSION HAS BEEN PROVIDED SEPARATELY. VERIFICATION: – Date and location verified by metadata on original file – Fence, light poles and airfield layout matched archive imagery
Boeing and 21 Air also said they would support government investigations.
21 Air said it was devastated by the accident and expressed condolences to the families and loved ones of those who died.
The crash is not the first fatal accident involving an aircraft operating for Amazon Prime Air. In February 2019, Atlas Air Flight 3591, a Boeing 767-300 freighter flying for Amazon Prime Air from Miami to Houston, entered a rapid descent and crashed into Trinity Bay in Texas. All three people aboard were killed.